Publications

2020

Key, Felix M.; Posth, Cosimo; Esquivel-Gomez, Luis R.; Hübler, Ron; Spyrou, Maria A.; Neumann, Gunnar U.; Furtwängler, Anja; Sabin, Susanna; Burri, Marta; Wissgott, Antje; Lankapalli, Aditya Kumar; Vågene, Åshild J.; Meyer, Matthias; Nagel, Sarah; Tukhbatova, Rezeda; Khokhlov, Aleksandr; Chizhevsky, Andrey; Hansen, Svend; Belinsky, Andrey B.; Kalmykov, Alexey; Kantorovich, Anatoly R.; Maslov, Vladimir E.; Stockhammer, Philipp W.; Vai, Stefania; Zavattaro, Monica; Riga, Alessandro; Caramelli, David; Skeates, Robin; Beckett, Jessica; Gradoli, Maria Giuseppina; Steuri, Noah; Hafner, Albert; Ramstein, Marianne; Siebke, Inga; Lösch, Sandra; Erdal, Yilmaz Selim; Alikhan, Nabil-Fareed; Zhou, Zhemin; Achtman, Mark; Bos, Kirsten; Reinhold, Sabine; Haak, Wolfgang; Kühnert, Denise; Herbig, Alexander; Krause, Johannes (2020): Emergence of human-adapted Salmonella enterica is linked to the Neolithization process. In: Nature ecology & evolution 4 (3), S. 324–333. DOI: 10.1038/s41559-020-1106-9. Read Free2read

2019

Hübler*, Ron; Key*, Felix M.; Warinner, Christina; Bos, Kirsten I.; Krause, Johannes; Herbig, Alexander (2019): HOPS: automated detection and authentication of pathogen DNA in archaeological remains. In: Genome biology 20 (1), S. 280. DOI: 10.1186/s13059-019-1903-0. (*...equal contribution) Read

Reher, David; Key, Felix M.; Andrés, Aida M.; Kelso, Janet (2019): Immune Gene Diversity in Archaic and Present-day Humans. In: Genome biology and evolution 11 (1), S. 232–241. DOI: 10.1093/gbe/evy271. Read

Spyrou, Maria A.; Keller, Marcel; Tukhbatova, Rezeda I.; Scheib, Christiana L.; Nelson, Elizabeth A.; Andrades Valtueña, Aida; Neumann, Gunnar U.; Walker, Don; Alterauge, Amelie; Carty, Niamh; Cessford, Craig; Fetz, Hermann; Gourvennec, Michaël; Hartle, Robert; Henderson, Michael; Heyking, Kristin von; Inskip, Sarah A.; Kacki, Sacha; Key, Felix M.; Knox, Elizabeth L.; Later, Christian; Maheshwari-Aplin, Prishita; Peters, Joris; Robb, John E.; Schreiber, Jürgen; Kivisild, Toomas; Castex, Dominique; Lösch, Sandra; Harbeck, Michaela; Herbig, Alexander; Bos, Kirsten I.; Krause, Johannes (2019): Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes. In: Nature communications 10 (1), S. 4470. DOI: 10.1038/s41467-019-12154-0. Read

2018

Key, Felix M.; Abdul-Aziz, Muslihudeen A.; Mundry, Roger; Peter, Benjamin M.; Sekar, Aarthi; D'Amato, Mauro; Dennis, Megan Y.; Schmidt, Joshua M.; Andrés, Aida M. (2018): Human local adaptation of the TRPM8 cold receptor along a latitudinal cline. In: PLoS genetics 14 (5), e1007298. DOI: 10.1371/journal.pgen.1007298. Read

Krause-Kyora, Ben; Susat, Julian; Key, Felix M.; Kühnert, Denise; Bosse, Esther; Immel, Alexander; Rinne, Christoph; Kornell, Sabin-Christin; Yepes, Diego; Franzenburg, Sören; Heyne, Henrike O.; Meier, Thomas; Lösch, Sandra; Meller, Harald; Friederich, Susanne; Nicklisch, Nicole; Alt, Kurt W.; Schreiber, Stefan; Tholey, Andreas; Herbig, Alexander; Nebel, Almut; Krause, Johannes (2018): Neolithic and medieval virus genomes reveal complex evolution of hepatitis B. In: eLife 7. DOI: 10.7554/eLife.36666. Read

2017

Andrades Valtueña, Aida; Mittnik, Alissa; Key, Felix M.; Haak, Wolfgang; Allmäe, Raili; Belinskij, Andrej; Daubaras, Mantas; Feldman, Michal; Jankauskas, Rimantas; Janković, Ivor; Massy, Ken; Novak, Mario; Pfrengle, Saskia; Reinhold, Sabine; Šlaus, Mario; Spyrou, Maria A.; Szécsényi-Nagy, Anna; Tõrv, Mari; Hansen, Svend; Bos, Kirsten I.; Stockhammer, Philipp W.; Herbig, Alexander; Krause, Johannes (2017): The Stone Age Plague and Its Persistence in Eurasia. In: Current biology : CB 27 (23), 3683-3691.e8. DOI: 10.1016/j.cub.2017.10.025. Read

Key, Felix M.; Posth, Cosimo; Krause, Johannes; Herbig, Alexander; Bos, Kirsten I. (2017): Mining Metagenomic Data Sets for Ancient DNA: Recommended Protocols for Authentication. In: Trends in genetics : TIG 33 (8), S. 508–520. DOI: 10.1016/j.tig.2017.05.005. Read

Prüfer, Kay; Filippo, Cesare de; Grote, Steffi; Mafessoni, Fabrizio; Korlević, Petra; Hajdinjak, Mateja; Vernot, Benjamin; Skov, Laurits; Hsieh, Pinghsun; Peyrégne, Stéphane; Reher, David; Hopfe, Charlotte; Nagel, Sarah; Maricic, Tomislav; Fu, Qiaomei; Theunert, Christoph; Rogers, Rebekah; Skoglund, Pontus; Chintalapati, Manjusha; Dannemann, Michael; Nelson, Bradley J.; Key, Felix M.; Rudan, Pavao; Kućan, Željko; Gušić, Ivan; Golovanova, Liubov V.; Doronichev, Vladimir B.; Patterson, Nick; Reich, David; Eichler, Evan E.; Slatkin, Montgomery; Schierup, Mikkel H.; Andrés, Aida M.; Kelso, Janet; Meyer, Matthias; Pääbo, Svante (2017): A high-coverage Neandertal genome from Vindija Cave in Croatia. In: Science (New York, N.Y.) 358 (6363), S. 655–658. DOI: 10.1126/science.aao1887. Read

2016

Filippo, Cesare de; Key, Felix M.; Ghirotto, Silvia; Benazzo, Andrea; Meneu, Juan R.; Weihmann, Antje; Parra, Genís; Green, Eric D.; Andrés, Aida M. (2016): Recent Selection Changes in Human Genes under Long-Term Balancing Selection. In: Molecular biology and evolution 33 (6), S. 1435–1447. DOI: 10.1093/molbev/msw023. Read

Key, Felix M.; Fu, Qiaomei; Romagné, Frédéric; Lachmann, Michael; Andrés, Aida M. (2016): Human adaptation and population differentiation in the light of ancient genomes. In: Nature communications 7, S. 10775. DOI: 10.1038/ncomms10775. Read

2014

Key, Felix M.; Peter, Benjamin; Dennis, Megan Y.; Huerta-Sánchez, Emilia; Tang, Wei; Prokunina-Olsson, Ludmila; Nielsen, Rasmus; Andrés, Aida M. (2014): Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4). In: PLoS genetics 10 (10), e1004681. DOI: 10.1371/journal.pgen.1004681. Read

Key*, Felix M.; Teixeira*, João C.; Filippo, Cesare de; Andrés, Aida M. (2014): Advantageous diversity maintained by balancing selection in humans. In: Current opinion in genetics & development 29, S. 45–51. DOI: 10.1016/j.gde.2014.08.001. (*...equal contribution) Read

2011

Lehnertz, Bernhard; Rogalski, Jason C.; Schulze, Felix M.; Yi, Lin; Lin, Shujun; Kast, Jürgen; Rossi, Fabio M. V. (2011): p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice. In: Molecular cell 43 (4), S. 673–680. DOI: 10.1016/j.molcel.2011.08.006. Read

2010

Stittrich, Anna-Barbara; Haftmann, Claudia; Sgouroudis, Evridiki; Kühl, Anja Andrea; Hegazy, Ahmed Nabil; Panse, Isabel; Riedel, Rene; Flossdorf, Michael; Dong, Jun; Fuhrmann, Franziska; Heinz, Gitta Anne; Fang, Zhuo; Li, Na; Bissels, Ute; Hatam, Farahnaz; Jahn, Angelina; Hammoud, Ben; Matz, Mareen; Schulze, Felix-Michael; Baumgrass, Ria; Bosio, Andreas; Mollenkopf, Hans-Joachim; Grün, Joachim; Thiel, Andreas; Chen, Wei; Höfer, Thomas; Loddenkemper, Christoph; Löhning, Max; Chang, Hyun-Dong; Rajewsky, Nikolaus; Radbruch, Andreas; Mashreghi, Mir-Farzin (2010): The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. In: Nature immunology 11 (11), S. 1057–1062. DOI: 10.1038/ni.1945. Read