Publications

1        Majer, O.*, Liu, B.*, Kreuk, L .S .M., Krogan, N. & Barton, G. M. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity. Nature, doi:10.1038/s41586-019-1612-6 (2019). *authors contributed equally.

2        Majer, O., Liu, B., Woo, B. J., Kreuk, L .S .M., Van Dis, E. & Barton, G. M. Release from UNC93B1 reinforces the compartmentalized activation of select TLRs. Nature, doi:10.1038/s41586-019-1611-7 (2019).

3        Majer, O., Liu, B. & Barton, G. M. Nucleic acid-sensing TLRs: trafficking and regulation. Curr Opin Immunol 44, 26-33, (2017).

4        Koprulu, A. D., Kastner, R., Wienerroither, S., Lassnig, C., Putz, E. M., Majer, O., Reutterer, B., Sexl, V., Kuchler, K., Muller, M., Decker, T. & Ellmeier, W. The tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infection. PLoS One 8, e60476, (2013).

5        Zavrel, M., Majer, O., Kuchler, K. & Rupp, S. Transcription factor Efg1 shows a haploinsufficiency phenotype in modulating the cell wall architecture and immunogenicity of Candida albicans. Eukaryot Cell 11, 129-140, (2012).

6        Majer, O., Bourgeois, C., Zwolanek, F., Lassnig, C., Kerjaschki, D., Mack, M., Muller, M. & Kuchler, K. Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections. PLoS Pathog 8, e1002811, (2012).

7        Seider, K., Brunke, S., Schild, L., Jablonowski, N., Wilson, D., Majer, O., Barz, D., Haas, A., Kuchler, K., Schaller, M. & Hube, B. The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. J Immunol 187, 3072-3086, (2011).

8        Bourgeois, C., Majer, O., Frohner, I. E., Lesiak-Markowicz, I., Hildering, K. S., Glaser, W., Stockinger, S., Decker, T., Akira, S., Muller, M. & Kuchler, K. Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-beta signaling. J Immunol 186, 3104-3112, (2011).

9        Bourgeois, C., Majer, O., Frohner, I. E., Tierney, L. & Kuchler, K. Fungal attacks on mammalian hosts: pathogen elimination requires sensing and tasting. Curr Opin Microbiol 13, 401-408, (2010).

10     Hnisz, D., Majer, O., Frohner, I. E., Komnenovic, V. & Kuchler, K. The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog 6, e1000889, (2010).

11     Frohner, I. E., Bourgeois, C., Yatsyk, K., Majer, O. & Kuchler, K. Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance. Mol Microbiol 71, 240-252, (2009).

12     Bourgeois, C., Majer, O., Frohner, I. & Kuchler, K. In vitro systems for studying the interaction of fungal pathogens with primary cells from the mammalian innate immune system. Methods Mol Biol 470, 125-139, (2009).