Evolutionary Pathogenomics

Evolutionary Pathogenomics

Microbial pathogens are shaped by their evolutionary history, which provides them the genomic framework to cause disease. The Key lab aims to uncover the genetic mechanisms and phenotypic variation that underlay emergence and adaptation of infectious microbes. Therefore we develop methods to track microbial evolution on dramatically different timescales by leveraging ancient DNA from archaeological specimen as well as high definition genomic data from clinical samples. Understanding the mechanisms of infectious disease emergence and adaptation holds promise to improve disease prevention, intervention and to develop more targeted therapies. More details here

News

11/2020: Meike Soerensen joins us as a lab manager. Huge welcome Meike!

09/2020: Official start of the lab. Stay tuned for updates. Exciting times ahead.

04/2020: The Key lab has two open calls for PhD students part of the IMPRS-IDI grad school. Come and join us to work on exciting and interdisciplinary projects in bacterial genetics! Read more

02/2020: Our paper about human-pathogen emergence linked to the agricultural transition is published in Nature Ecol & Evol! Covered widely including Science, a News & Views, and the TWiM podcast.

12/2019: Our paper about HOPS is out in Genome Biology. We present a computational tool that facilitates streamlined identification and authentication of ancient microbial DNA from archaeological remains.

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