Innovative approaches towards a resistance-proof treatment of acute and chronic infections
Research report (imported) 2011 - Max Planck Institute for Infection Biology
Scientists at the institute pursue innovative approaches to develop resistance-proof cures of acute and chronic infections. The strategy relies on the fact that infections decisively depend on the cooperation of host cell determinants, which constitute druggable targets. With the help of modern RNAi based screening technology the entire human genome was scanned for determinants essential for the replication and growth of Influenza viruses and Chlamydiae. The resulting data form a basis for the design of novel drugs and vaccines and provide striking views on the biology of infection.