Tuberculosis: Research on a forgotten disease
Research report (imported) 2010 - Max Planck Institute for Infection Biology
Annually, 10 million individuals develop tuberculosis of whom 2 million die. Globally, an estimated 2 billion individuals are infected with the etiologic agent. New vaccines, drugs and diagnostics are urgently needed. Targeted research can make a difference. Our research reveals novel mechanisms of early host defense and provides insights into the granuloma as histologic correlate of protection and pathology. Further, we have developed a novel vaccine and characterized biomarkers for tuberculosis.