What Role Do Neutrophils Play in Infectious Disease?

Interview with MPIIB Director Arturo Zychlinsky by the science communication platform LATEST THINKING

July 09, 2020

What Role Do Neutrophils Play in Infectious Disease?


Neutrophils are among the first immune cells to go to a site of infection. In this video, MPIIB director Arturo Zychlinsky explores the role that Neutrophils play in infectious disease. Zychlinsky explains that Neutrophil Extracellular Traps (or NETs) kill and prevent the dissemination of microbes while also alerting other parts of the immune system to infection. Revealing some of the processes involved in NET formation, Zychlinsky demonstrates that, depending on the type of disease, NETs can play either a beneficial or a deleterious role. With NET’s relevance extending beyond infectious disease to conditions including cancer and cardiovascular disease, Zychlinsky’s work has opened up a fertile field of exploration for research labs worldwide.

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