Location location location: the physical properties of microbial ligands dictate the immune response
- Date: Oct 20, 2021
- Time: 04:00 PM (Local Time Germany)
- Speaker: Ivan Zanoni
- Harvard Medical School
- Location: Zoom video conference
- Host: Olivia Majer
- Contact: vseminars@mpiib-berlin.mpg.de
If you are interested in joining the seminar, please contact: vseminars@mpiib-berlin.mpg.de
Once registered, you will receive a zoom conference link 30 mins before the talk starts - please sign in using your full name.
Talk abstract:
A central paradigm of immunology is that the innate immune system first detects infectious agents in peripheral tissues, shortly after a pathogen has breached an epithelial barrier. This detection event is mediated by pattern recognition receptors in phagocytes, which then migrate to draining lymph nodes, where information of a microbial encounter is conveyed to T and B lymphocytes to generate adaptive immunity. Through the study of fungal moieties, I will present data that challenge this model.