Publications

Vllahu, M.; Voli, A.; Licursi, V.; Zagami, C.; D'Amore, A.; Traulsen, J.; Woelffling, S.; Schmid, M.; Crickley, R.; Lisle, R. et al.; Link, A.; Tosco, A.; Meyer, T. F.; Boccellato, F.: Inflammation promotes stomach epithelial defense by stimulating the secretion of antimicrobial peptides in the mucus. Gut Microbes 16 (1), 2390680 (2024)

Liu, S.; Wen, H.; Li, F.; Xue, X.; Sun, X.; Li, F.; Hu, R.; Xi, H.; Boccellato, F.; Meyer, T. F. et al.; Mi, Y.; Zheng, P.: Revealing the pathogenesis of gastric intestinal metaplasia based on the mucosoid air-liquid interface. J Transl Med 22 (1) (2024)

Liu, B.; Bukhari, I.; Li, F.; Ren, F.; Xia, X.; Hu, B.; Liu, H.; Meyer, T. F.; Marshall, B. J.; Tay, A. et al.; Fu, Y.; Wu, W.; Tang, Y.; Mi, Y.; Zheng, P.-Y.: Enhanced LRP8 expression induced by Helicobacter pylori drives gastric cancer progression by facilitating β-Catenin nuclear translocation. Journal of advanced research: JAR, S2090-1232(24)00131-0 (2024)

Kumar, N.; Prakash, P. G.; Wentland, C.; Kurian, S. M.; Jethva, G.; Brinkmann, V.; Mollenkopf, H.-J.; Krammer, T.; Toussaint, C.; Saliba, A.-E. et al.; Biebl, M.; Jürgensen, C.; Wiedenmann, B.; Meyer, T. F.; Gurumurthy, R. K.; Chumduri, C.: Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis. Nature Communications 15 (1), 3064 (2024)

#, J. L.; #, X. L.; Li, X.; Li, H.; Shi, L.; Xia, X.; He, B.-L.; Meyer, T. F.; Li, X.; Sun, H. et al.; Yang, X.: Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (4), e2311630121 (2024)

Dong, J.; Holthaus, D.; Peters, C.; Koster, S.; Ehsani, M.; Quevedo-Olmos, A.; Berger, H.; Zarobkiewicz, M.; Mangler, M.; Gurumurthy, R. K. et al.; Hedemann, N.; Chumduri, C.; Kabelitz, D.; Meyer, T. F.: γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids. Frontiers in Immunology 14, 1281646. (2023)

Fritsche, K.; Boccellato, F.; Schlaermann, P.; Koeppel, M.; Denecke, C.; Link, A.; Malfertheiner, P.; Gut, I.; Meyer, T. F.; Berger, H.: DNA methylation in human gastric epithelial cells defines regional identity without restricting lineage plasticity. Clin Epigenetics 14 (1), 193 (2022)

Eletto, D.; Mentucci, F.; Vllahu, M.; Voli, A.; Petrella, A.; Boccellato, F.; Meyer, T. F.; Porta, A.; Tosco, A.: IFNγ-dependent silencing of TFF1 during Helicobacter pylori infection. Open Biology 12 (12), 220278 (2022)

Eletto, D.; Mentucci, F.; Vllahu, M.; Voli, A.; Petrella, A.; Boccellato, F.; Meyer, T. F.; Porta, A.; Tosco, A.: IFN gamma-dependent silencing of TFF1 during Helicobacter pylori infection. Open Biology 12, 220278 (2022)

Gurumurthy, R. K.; Pleissner, K.-P.; Chumduri, C.; Meyer, T. F.; Mäurer, A. P.: Single object profiles regression analysis (SOPRA): a novel method for analyzing high-content cell-based screens. BMC Bioinformatics 23 (1), 440 (2022)

Gurumurthy, R. K.; Koster, S.; Kumar, N.; Meyer, T. F.; Chumduri, C.: Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection. Nature Protocols, 1030 (2022)

Kapalczynska, M.; Lin, M.; Maertzdorf, J.; Heuberger, J.; Muellerke, S.; Zuo, X.; Vidal, R.; Shureiqi, I.; Fischer, A.-S.; Sauer, S. et al.; Berger, H.; Kidess, E.; Mollenkopf, H.-J.; Tacke, F.; Meyer, T. F.; Sigal, M.: BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation. Nature Communications 13 (1), 1577 (2022)

Koster, S.; Gurumurthy, R. K.; Kumar, N.; Prakash, P. G.; Dhanraj, J.; Bayer, , S.; Berger, H.; Kurian, S. M.; Drabkina, M.; Mollenkopf, H.-J. et al.; Goosmann, C.; Brinkmann, V.; Nagel, Z.; Mangler, M.; Meyer, T. F.; Chumduri, C.: Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming. Nature Communications 13 (1) (2022)

Humbert, P. O.; Zoranovic Pryjda, T.; Pranjic, B.; Farrell, A.; Fujikura, K.; de Simoes, R. M.; Karim, R.; Kozieradzki, I.; Cronin, S. J. F.; Neely, G. G. et al.; Meyer, T. F.; Hagelkruys, A.; Richardson, H. E.; Penninger, J. M.: TSPAN6 is a suppressor of Ras-driven cancer. Oncogene (2022)

Berger, H.; Meyer, T. F.: Mechanistic dissection unmasks colibactin as a prevalent mutagenic driver of cancer. Cancer Cell 39 (11), pp. 1439 - 1441 (2021)

Wölffling, S.; Daddi, A. A.; Imai-Matsushima, A.; Fritsche, K.; Goosmann, C.; Traulsen, J.; Lisle, R.; Schmid, M.; Reines-Benassar, M. D. M.; Pfannkuch, L. et al.; Brinkmann, V.; Bornschein, J.; Malfertheiner, P.; Ordemann, J.; Link, A.; Meyer, T. F.; Boccellato, F.: EGF and BMPs Govern Differentiation and Patterning in Human Gastric Glands. Gastroenterology 161 (2), pp. 623 - 636 (2021)

Maubach, G.; Lim, M. C. C.; Sokolova, O.; Backert, S.; Meyer, T. F.; Naumann, M.: TIFA has dual functions in Helicobacter pylori-induced classical and alternative NF-κB pathways. EMBO Reports, e52878 (2021)

Rother, M.; Dimmler, C.; Weege, F.; Mollenkopf, H.-J.; Meyer, T. F.; Naumann, M.: Discovery of Zika virus host dependency factors in trophoblasts using CRISPR/Cas9 screening. Journal of Virological Methods 290, 114085 (2021)

Chumduri, C.; Gurumurthy, R. K.; Berger, H.; Dietrich, O.; Kumar, N.; Koster, S.; Brinkmann, V.; Hoffmann, K.; Drabkina, M.; Arampatzi, P. et al.; Son, D.; Klemm, U.; Mollenkopf, H.-J.; Herbst, H.; Mangler, M.; Vogel, J.; Saliba, A.-E.; Meyer, T. F.: Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia. Nature Cell Biology 23 (2), pp. 184 - 197 (2021)

Iftekhar, A.; Berger, H.; Bouznad, N.; Heuberger, J.; Boccellato, F.; Dobrindt, U.; Hermeking, H.; Sigal, M.; Meyer, T. F.: Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells. Nature Communications 12 (1), pp. 1 - 15 (2021)