Publications

Gurumurthy, R. K.; Koster, S.; Kumar, N.; Meyer, T. F.; Chumduri, C.: Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection. Nature Protocols, 1030 (2022)

Kapalczynska, M.; Lin, M.; Maertzdorf, J.; Heuberger, J.; Muellerke, S.; Zuo, X.; Vidal, R.; Shureiqi, I.; Fischer, A.-S.; Sauer, S. et al.; Berger, H.; Kidess, E.; Mollenkopf, H.-J.; Tacke, F.; Meyer, T. F.; Sigal, M.: BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation. Nature Communications 13 (1), 1577 (2022)

Koster, S.; Gurumurthy, R. K.; Kumar, N.; Prakash, P. G.; Dhanraj, J.; Bayer, , S.; Berger, H.; Kurian, S. M.; Drabkina, M.; Mollenkopf, H.-J. et al.; Goosmann, C.; Brinkmann, V.; Nagel, Z.; Mangler, M.; Meyer, T. F.; Chumduri, C.: Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming. Nature Communications 13 (1) (2022)

Humbert, P. O.; Zoranovic Pryjda, T.; Pranjic, B.; Farrell, A.; Fujikura, K.; de Simoes, R. M.; Karim, R.; Kozieradzki, I.; Cronin, S. J. F.; Neely, G. G. et al.; Meyer, T. F.; Hagelkruys, A.; Richardson, H. E.; Penninger, J. M.: TSPAN6 is a suppressor of Ras-driven cancer. Oncogene (2022)

Berger, H.; Meyer, T. F.: Mechanistic dissection unmasks colibactin as a prevalent mutagenic driver of cancer. Cancer Cell 39 (11), pp. 1439 - 1441 (2021)

Wölffling, S.; Daddi, A. A.; Imai-Matsushima, A.; Fritsche, K.; Goosmann, C.; Traulsen, J.; Lisle, R.; Schmid, M.; Reines-Benassar, M. D. M.; Pfannkuch, L. et al.; Brinkmann, V.; Bornschein, J.; Malfertheiner, P.; Ordemann, J.; Link, A.; Meyer, T. F.; Boccellato, F.: EGF and BMPs Govern Differentiation and Patterning in Human Gastric Glands. Gastroenterology 161 (2), pp. 623 - 636 (2021)

Maubach, G.; Lim, M. C. C.; Sokolova, O.; Backert, S.; Meyer, T. F.; Naumann, M.: TIFA has dual functions in Helicobacter pylori-induced classical and alternative NF-κB pathways. EMBO Reports, e52878 (2021)

Rother, M.; Dimmler, C.; Weege, F.; Mollenkopf, H.-J.; Meyer, T. F.; Naumann, M.: Discovery of Zika virus host dependency factors in trophoblasts using CRISPR/Cas9 screening. Journal of Virological Methods 290, 114085 (2021)

Chumduri, C.; Gurumurthy, R. K.; Berger, H.; Dietrich, O.; Kumar, N.; Koster, S.; Brinkmann, V.; Hoffmann, K.; Drabkina, M.; Arampatzi, P. et al.; Son, D.; Klemm, U.; Mollenkopf, H.-J.; Herbst, H.; Mangler, M.; Vogel, J.; Saliba, A.-E.; Meyer, T. F.: Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia. Nature Cell Biology 23 (2), pp. 184 - 197 (2021)

Iftekhar, A.; Berger, H.; Bouznad, N.; Heuberger, J.; Boccellato, F.; Dobrindt, U.; Hermeking, H.; Sigal, M.; Meyer, T. F.: Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells. Nature Communications 12 (1), pp. 1 - 15 (2021)

Dekel, N.; Eisenberg-Domovich, Y.; Karlas, A.; Meyer, T. F.; Bracher, F.; Lebendiker, M.; Danieli, T.; Livnah, O.: Expression, purification and crystallization of CLK1 kinase – A potential target for antiviral therapy. Protein Expression and Purification 176, 105742 (2020)

Bauer, M.; Nascakova, Z.; Mihai, A.-I.; Cheng, P. F.; Levesque, M. P.; Lampart, S.; Hurwitz, R.; Pfannkuch, L.; Dobrovolna, J.; Jacobs, M. et al.; Bartfeld, S.; Dohlman, A.; Shen, X.; Gall, A. A.; Salama, N. R.; Töpfer, A.; Weber, A.; Meyer, T. F.; Janscak, P.; Müller, A.: The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress. Nature Communications 11 (1), 5117 (2020)

Sepe, L. P.; Hartl, K.; Iftekhar, A.; Berger, H.; Kumar, N.; Goosmann, C.; Chopra, S.; Schmidt, S. C.; Gurumurthy, R. K.; Meyer, T. F. et al.; Boccellato, F.: Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells. mBio 11 (5), 01911-20. (2020)

Estibariz, I.; Ailloud, F.; Woltemate, S.; Bunk, B.; Spröer, C.; Overmann, J.; Aebischer, T.; Meyer, T. F.; Josenhans, C.; Suerbaum, S.: In Vivo Genome and Methylome Adaptation of cag-Negative Helicobacter pylori during Experimental Human Infection. mBio 11 (4), 01803-20 (2020)

Dziubanska-Kusibab, P. J.; Berger, H.; Battistini, F.; Bouwman, B. A. M.; Iftekhar, A.; Katainen, R.; Cajuso, T.; Crosetto, N.; Orozco, M.; Aaltonen, L. A. et al.; Meyer, T. F.: Colibactin DNA-damage signature indicates mutational impact in colorectal cancer. Nature Medicine 26 (7), pp. 1063 - 1069 (2020)

Xavier, A.; Al-Zeer, M. A.; Meyer, T. F.; Daumke, O.: hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis. Cell Reports 31 (7), 107667 (2020)

Hoffmann, K.; Berger, H.; Kulbe, H.; Thillainadarasan, S.; Mollenkopf, H.-J.; Zemojtel, T.; Taube, E.; Darb-Esfahani, S.; Mangler, M.; Sehouli, J. et al.; Chekerov, R.; Braicu, E. I.; Meyer, T. F.; Kessler, M.: Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment. EMBO Journal 39 (6), e104013 (2020)

Wang, D.; He, J.; Dong, J.; Meyer, T. F.; Xu, T.: The HIPPO pathway in gynecological malignancies. American journal of cancer research 10 (2), pp. 610 - 629 (2020)

Nachreiner, I.; Hussain, A. F.; Wullner, U.; Machuy, N.; Meyer, T. F.; Fischer, R.; Gattenlöhner, S.; Meinhold-Heerlein, I.; Barth, S.; Tur, M. K.: Elimination of HER3-expressing breast cancer cells using aptamer-siRNA chimeras. Experimental and Therapeutic Medicine 18 (4), pp. 2401 - 2412 (2019)

Harnack, C.; Berger, H.; Antanaviciute, A.; Vidal, R.; Sauer, S.; Simmons, A.; Meyer, T. F.; Sigal, M.: R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon. Nature Communications 10 (1), 4368 (2019)