Publications of Thumbi Ndung'u

Laher, F.; Ranasinghe, S.; Porichis, F.; Mewalal, N.; Pretorius, K.; Ismail, N.; Buus, S.; Stryhn, A.; Carrington, M.; Walker, B. D. et al.; Ndung'u, T.; Ndhlovu, Z. M.: HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer+ Gag-Specific CD4+ T Cells in Chronic Clade C HIV-1 Infection. Journal of Virology 91 (7), e02477-16 (2017)

Chang, C. C.; Kangethe, R.; Omarjee, S.; Hiramen, K.; Gosnell, B.; Sojane, K.; Moosa, M.-Y. S.; Lewin, S. R.; French, M. A.; Ndung'u, T.: Relationship of Human Immunodeficiency Virus Viral Load in Cerebrospinal Fluid and Plasma in Patients Co-infected With Cryptococcal Meningitis. Open Forum Infectious Diseases 4 (2), ofx032 (2017)

Thobakgale, C.; Naidoo, K.; McKinnon, L. R.; Werner, L.; Samsunder, N.; Karim, S. A.; Ndung'u, T.; Altfeld, M.; Naidoo, K.: Interleukin 1-Beta (IL-1) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients. Journal of Acquired Immune Deficiency Syndromes 74 (2), pp. 213 - 220 (2017)

Wong, E. B.; Ndung'u, T.; Kasprowicz, V. O.: The role of mucosal-associated invariant T cells in infectious diseases. Immunology 150 (1), pp. 45 - 54 (2017)

Muenchhoff, M.; Adland, E.; Karimanzira, O.; Crowther, C.; Pace, M.; Csala, A.; Leitman, E.; Moonsamy, A.; McGregor, C.; Hurst, J. et al.; Groll, A.; Mori, M.; Sinmyee, S.; Thobakgale, C.; Tudor-Williams, G.; Prendergast, A. J.; Kloverpris, H.; Roider, J.; Leslie, A.; Shingadia, D.; Brits, T.; Daniels, S.; Frater, J.; Willberg, C. B.; Walker, B. D.; Ndung'u, T.; Jooste, P.; Moore, P. L.; Morris, L.; Goulder, P.: Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection. Science Translational Medicine 8 (358), 358ra125 (2016)

Tsai, M.-H.; Muenchhoff, M.; Adland, E.; Carlqvist, A.; Roider, J.; Cole, D. K.; Sewell, A. K.; Carlson, J.; Ndung'u, T.; Goulder, P. J. R.: Paediatric non-progression following grandmother-to-child HIV transmission. Retrovirology 13 (1), 65 (2016)

Koofhethile, C. K.; Ndhlovu, Z. M.; Thobakgale-Tshabalala, C.; Prado, J. G.; Ismail, N.; Mncube, Z.; Mkhize, L.; van der Stok, M.; Yende, N.; Walker, B. D. et al.; Goulder, P. J. R.; Ndung'u, T.: CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles. Journal of Virology 90 (15), pp. 6818 - 6831 (2016)

Leitman, E. M.; Hurst, J.; Mori, M.; Kublin, J.; Ndung'u, T.; Walker, B. D.; Carlson, J.; Gray, G. E.; Matthews, P. C.; Frahm, N. et al.; Goulder, P. J.R.: Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02. The Journal of Infectious Diseases 214 (3), pp. 379 - 389 (2016)

Reddy, K.; Ooms, M.; Letko, M.; Garrett, N.; Simon, V.; Ndung'u, T.: Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes. AIDS 30 (11), pp. 1723 - 1729 (2016)

Carlson, J. M.; Du, V. Y.; Pfeifer, N.; Bansal, A.; Tan, V. Y. F.; Power, K.; Brumme, C. J.; Kreimer, A.; DeZiel, C. E.; Fusi, N. et al.; Schaefer, M.; Brockman, M. A.; Gilmour, J.; Price, M. A.; Kilembe, W.; Haubrich, R.; John, M.; Mallal, S.; Shapiro, R.; Frater, J.; Harrigan, P. R.; Ndung'u, T.; Allen, S.; Heckerman, D.; Sidney, J.; Allen, T. M.; Goulder, P. J. R.; Brumme, Z. L.; Hunter, E.; Goepfert, P. A.: Impact of pre-adapted HIV transmission. Nature Medicine 22 (6), pp. 606 - 613 (2016)

Matthews, P. C.; Carlson, J. M.; Beloukas, A.; Malik, A.; Jooste, P.; Ogwu, A.; Shapiro, R.; Riddell, L.; Chen, F.; Luzzi, G. et al.; Jesuthasan, G.; Jeffery, K.; Jojic, N.; Ndung'u, T.; Carrington, M.; Goulder, P. J. R.; Geretti, A. M.; Klenerman, P.: HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults. Journal of Infectious Diseases 213 (8), pp. 1248 - 1252 (2016)

Jaggernath, M.; Naicker, R.; Madurai, S.; Brockman, M. A.; Ndung'u, T.; Gelderblom, H. C.: Diagnostic Accuracy of the HemoCue Hb 301, STAT-Site MHgb and URIT-12 Point-of-Care Hemoglobin Meters in a Central Laboratory and a Community Based Clinic in Durban, South Africa. PLoS One 11 (4), e0152184 (2016)

Byrne, E. H.; Anahtar, M. N.; Cohen, K. E.; Moodley, A.; Padavattan, N.; Ismail, N.; Bowman, B. A.; Olson, G. S.; Mabhula, A.; Leslie, A. et al.; Ndung'u, T.; Walker, B. D.; Ghebremichael, M. S.; Dong, K. L.; Kwon, D. S.: Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study. Lancet Infectious Diseases 16 (4), pp. 441 - 448 (2016)

Danaviah, S.; de Oliveira, T.; Gordon, M.; Govender, S.; Chelule, P.; Pillay, S.; Naicker, T.; Cassol, S.; Ndung'u, T.: Analysis of Dominant HIV Quasispecies Suggests Independent Viral Evolution Within Spinal Granulomas Coinfected with Mycobacterium tuberculosis and HIV-1 Subtype C. AIDS Research and Human Retroviruses 32 (3), pp. 262 - 270 (2016)

Kløverpris, H. N.; Kazer, S. W.; Mjösberg, J.; Mabuka, J. M.; Wellmann, A.; Ndhlovu, Z.; Yadon, M. C.; Nhamoyebonde, S.; Muenchhoff, M.; Simoni, Y. et al.; Andersson, F.; Kuhn, W.; Garrett, N.; Burgers, W. A.; Kamya, P.; Pretorius, K.; Dong, K.; Moodley, A.; Newell, E. W.; Kasprowicz, V.; Karim, S. S. A.; Goulder, P.; Shalek, A. K.; Walker, B. D.; Ndung'u, T.; Leslie, A.: Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression. Immunity 44 (2), pp. 391 - 405 (2016)

Kasprowicz, V. O.; Cheng, T.-Y.; Ndung'u, T.; Sunpath, H.; Moody, D. B.; Kasmar, A. G.: HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids. The Journal of Infectious Diseases 213 (4), pp. 628 - 633 (2016)

Naranbhai, V.; de Assis Rosa, D.; Werner, L.; Moodley, R.; Hong, H.; Kharsany, A.; Mlisana, K.; Sibeko, S.; Garrett, N.; Chopera, D. et al.; Carr, W. H.; Karim, Q. A.; Hill, A. V. S.; Karim, S. S. A.; Altfeld, M.; Gray, C. M.; Ndung'u, T.: Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women. BMC Infectious Diseases 16 (1), 27 (2016)

Pan, S.-J.; Tapley, A.; Adamson, J.; Little, T.; Urbanowski, M.; Cohen, K.; Pym, A.; Almeida, D.; Dorasamy, A.; Layre, E. et al.; Young, D. C.; Singh, R.; Patel, V. B.; Wallengren, K.; Ndung'u, T.; Wilson, D.; Moody, D. B.; Bishai, W.: Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules. The Journal of Infectious Diseases 212 (11), pp. 1827 - 1834 (2015)

Mann, J. K.; Omarjee, S.; Khumalo, P.; Ndung'u, T.: Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C. Virology Journal 12, 200 (2015)

Hölzemer, A.; Thobakgale, C. F.; Cruz, C. A. J.; Garcia-Beltran, W. F.; Carlson, J. M.; van Teijlingen, N. H.; Mann, J. K.; Jaggernath, M.; Kang, S.-g.; Körner, C. et al.; Chung, A. W.; Schafer, J. L.; Evans, D. T.; Alter, G.; Walker, B. D.; Goulder, P. J.; Carrington, M.; Hartmann, P.; Pertel, T.; Zhou, R.; Ndung'u, T.; Altfeld, M.: Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa. PLoS Medicine 12 (11), e1001900 (2015)