Publications of Thumbi Ndung'u

Ndhlovu, Z. M.; Kamya, P.; Mewalal, N.; Kløverpris, H. N.; Nkosi, T.; Pretorius, K.; Laher, F.; Ogunshola, F.; Chopera, D.; Shekhar, K. et al.; Ghebremichael, M.; Ismail, N.; Moodley, A.; Malik, A.; Leslie, A.; Goulder, P. J.R.; Buus, S.; Chakraborty, A.; Dong, K.; Ndung'u, T.; Walker, B. D.: Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point. Immunity 43 (3), pp. 591 - 604 (2015)

Matthews, P. C.; Beloukas, A.; Malik, A.; Carlson, J. M.; Jooste, P.; Ogwu, A.; Shapiro, R.; Riddell, L.; Chen, F.; Luzzi, G. et al.; Jaggernath, M.; Jesuthasan, G.; Jeffery, K.; Ndung'u, T.; Goulder, P. J. R.; Geretti, A. M.; Klenerman, P.: Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana. PLoS One 10 (7), e0134037 (2015)

Mori, M.; Adland, E.; Paioni, P.; Swordy, A.; Mori, L.; Laker, L.; Muenchhoff, M.; Matthews, P. C.; Tudor-Williams, G.; Lavandier, N. et al.; van Zyl, A.; Hurst, J.; Walker, B. D.; Ndung'u, T.; Prendergast, A.; Goulder, P.; Jooste, P.: Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection. PLoS One 10 (7), e0131591 (2015)

Adland, E.; Paioni, P.; Thobakgale, C.; Laker, L.; Mori, L.; Muenchhoff, M.; Csala, A.; Clapson, M.; Flynn, J.; Novelli, V. et al.; Hurst, J.; Naidoo, V.; Shapiro, R.; Huang, K.-H. G.; Frater, J.; Prendergast, A.; Prado, J. G.; Ndung'u, T.; Walker, B. D.; Carrington, M.; Jooste, P.; Goulder, P. J. R.: Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection. PLoS Pathogens 11 (6), e1004954 (2015)

Xu, G. J.; Kula, T.; Xu, Q.; Li, M. Z.; Vernon, S. D.; Ndung'u, T.; Ruxrungtham, K.; Sanchez, J.; Brander, C.; Chung, R. T. et al.; O’Connor, K. C.; Walker, B.; Larman, H. B.; Elledge, S. J.: Comprehensive serological profiling of human populations using a synthetic human virome. Science 348 (6239), aaa0698 (2015)

Kløverpris, H. N.; McGregor, R.; McLaren, J. E.; Ladell, K.; Harndahl, M.; Stryhn, A.; Carlson, J. M.; Koofhethile, C.; Gerritsen, B.; Keşmir, C. et al.; Chen, F.; Riddell, L.; Luzzi, G.; Leslie, A.; Walker, B. D.; Ndung'u, T.; Buus, S.; Price, D. A.; Goulder, P. J.: CD8+ TCR Bias and Immunodominance in HIV-1 Infection. The Journal of Immunology 194 (111), pp. 5329 - 5345 (2015)

Chetty, S.; Govender, P.; Zupkosky, J.; Pillay, M.; Ghebremichael, M.; Moosa, M.-Y. S.; Ndung'u, T.; Porichis, F.; Kasprowicz, V. O.: Co-Infection with Mycobacterium tuberculosis Impairs HIV-Specific CD8+ and CD4+ T Cell Functionality. PLoS One 10 (3), e0118654 (2015)

Gounder, K.; Padayachi, N.; Mann, J. K.; Radebe, M.; Mokgoro, M.; van der Stok, M.; Mkhize, L.; Mncube, Z.; Jaggernath, M.; Reddy, T. et al.; Walker, B. D.; Ndung'u, T.: High Frequency of Transmitted HIV-1 Gag HLA Class I-Driven Immune Escape Variants but Minimal Immune Selection over the First Year of Clade C Infection. PLoS One 10 (3), e0119886 (2015)

Sullivan, Z. A.; Wong, E. B.; Ndung'u, T.; Kasprowicz, V. O.; Bishai, W. R.: Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV. EBioMedicine 2 (4), pp. 334 - 340 (2015)

Mann, J. K.; Ndung'u, T.: HIV-1 vaccine immunogen design strategies. Virology Journal 12 (1), 3 (2015)

Radebe , M.; Gounder , K.; Mokgoro, M.; Ndhlovu , Z. M.; Mncube, Z.; Mkhize, L.; van der Stok, M.; Jaggernath, M.; Walker, B. D.; Ndung'u, T.: Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection. AIDS 29 (1), pp. 23 - 33 (2015)

Mahabeer, Y.; Chang, C. C.; Naidu, D.; Dorasamy, A.; Lewin, S.; Ndung'u, T.; Moosa, M.-Y.; French, M.; Mlisana, K.; Coovadia, Y.: Comparison of Etests and Vitek 2® to broth microdilution for the susceptibility testing of Cryptococcus neoformans. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 80 (4), pp. 294 - 298 (2014)

Demeulemeester, J.; Vets, S.; Schrijvers, R.; Madlala, P.; Maeyer, M. D.; Rijck, J. D.; Ndung'u, T.; Debyser, Z.; Gijsbers, R.: HIV-1 Integrase Variants Retarget Viral Integration and Are Associated with Disease Progression in a Chronic Infection Cohort. Cell Host & Microbe 16 (5), pp. 651 - 662 (2014)

Mann, J. K.; Chopera, D.; Omarjee, S.; Kuang, X. T.; Le, A. Q.; Anmole, G.; Danroth, R.; Mwimanzi, P.; Reddy, T.; Carlson, J. et al.; Radebe, M.; Goulder, P. J.R.; Walker, B. D.; Karim, S. A.; Novitsky, V.; Williamson, C.; Brockman, M. A.; Brumme, Z. L.; Ndung'u, T.: Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: Association with disease progression and influence of immune pressure. Virology 468-470, pp. 214 - 225 (2014)

Patel, V. B.; Connolly, C.; Singh, R.; Lenders, L.; Matinyenya, B.; Theron, G.; Ndung'u, T.; Dheda, K.: Comparison of Amplicor and GeneXpert MTB/RIF Tests for Diagnosis of Tuberculous Meningitis. Journal of Clinical Microbiology 52 (10), pp. 3777 - 3780 (2014)

Muenchhoff, M.; Madurai, S.; Hempenstall, A. J.; Adland, E.; Carlqvist, A.; Moonsamy, A.; Jaggernath, M.; Mlotshwa, B.; Siboto, E.; Ndung'u, T. et al.; Goulder, P. J. R.: Evaluation of the NucliSens EasyQ v2.0 Assay in Comparison with the Roche Amplicor v1.5 and the Roche CAP/CTM HIV-1 Test v2.0 in Quantification of C-Clade HIV-1 in Plasma. PLoS One 9 (8), e103983 (2014)

Mann, J. K.; Barton, J. P.; Ferguson, A. L.; Omarjee, S.; Walker, B. D.; Chakraborty, A.; Ndung'u, T.: The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing. PLoS Computational Biology 10 (8), e1003776 (2014)

Carlson, J. M.; Schaefer, M.; Monaco, D. C.; Batorsky, R.; Claiborne, D. T.; Prince, J.; Deymier, M. J.; Ende, Z. S.; Klatt, N. R.; DeZiel, C. E. et al.; Lin, T.-H.; Peng, J.; Seese, A. M.; Shapiro, R.; Frater, J.; Ndung'u, T.; Tang, J.; Goepfert, P.; Gilmour, J.; Price, M. A.; Kilembe, W.; Heckerman, D.; Goulder, P. J. R.; Allen, T. M.; Allen, S.; Hunter, E.: Selection bias at the heterosexual HIV-1 transmission bottleneck. Science 345 (6193), 1254031 (2014)

Kløverpris, H. N.; Adland, E.; Koyanagi, M.; Stryhn, A.; Harndahl, M.; Matthews, P. C.; Shapiro, R.; Walker, B. D.; Ndung'u, T.; Brander, C. et al.; Takiguchi, M.; Buus, S.; Goulder, P.: HIV Subtype Influences HLA-B*07:02-Associated HIV Disease Outcome. AIDS Research and Human Retroviruses 30 (5), pp. 468 - 475 (2014)

Naranbhai, V.; Chang, C. C.; Durgiah, R.; Omarjee, S.; Lim, A.; Moosa, M.-Y. S.; Elliot , J. H.; Ndung'u, T.; Lewin , S. R.; French, M. A. et al.; Carr, W. H.: Compartmentalization of innate immune responses in the central nervous system during cryptococcal meningitis/HIV coinfection. AIDS 28 (5), pp. 657 - 666 (2014)