Publications of Hilmar Berger

Dong, J.; Holthaus, D.; Peters, C.; Koster, S.; Ehsani, M.; Quevedo-Olmos, A.; Berger, H.; Zarobkiewicz, M.; Mangler, M.; Gurumurthy, R. K. et al.; Hedemann, N.; Chumduri, C.; Kabelitz, D.; Meyer, T. F.: γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids. Frontiers in Immunology 14, 1281646. (2023)

Fritsche, K.; Boccellato, F.; Schlaermann, P.; Koeppel, M.; Denecke, C.; Link, A.; Malfertheiner, P.; Gut, I.; Meyer, T. F.; Berger, H.: DNA methylation in human gastric epithelial cells defines regional identity without restricting lineage plasticity. Clin Epigenetics 14 (1), 193 (2022)

Fischer, A.-S.; Müllerke, S.; Arnold, A.; Heuberger, J.; Berger, H.; Lin, M.; Mollenkopf, H.-J.; Wizenty, J.; Horst, D.; Tacke, F. et al.; Sigal, M.: R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice. The Journal of Clinical Investigation 132 (21), e151363 (2022)

Kapalczynska, M.; Lin, M.; Maertzdorf, J.; Heuberger, J.; Muellerke, S.; Zuo, X.; Vidal, R.; Shureiqi, I.; Fischer, A.-S.; Sauer, S. et al.; Berger, H.; Kidess, E.; Mollenkopf, H.-J.; Tacke, F.; Meyer, T. F.; Sigal, M.: BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation. Nature Communications 13 (1), 1577 (2022)

Koster, S.; Gurumurthy, R. K.; Kumar, N.; Prakash, P. G.; Dhanraj, J.; Bayer, , S.; Berger, H.; Kurian, S. M.; Drabkina, M.; Mollenkopf, H.-J. et al.; Goosmann, C.; Brinkmann, V.; Nagel, Z.; Mangler, M.; Meyer, T. F.; Chumduri, C.: Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming. Nature Communications 13 (1) (2022)

Chumduri, C.; Gurumurthy, R. K.; Berger, H.; Dietrich, O.; Kumar, N.; Koster, S.; Brinkmann, V.; Hoffmann, K.; Drabkina, M.; Arampatzi, P. et al.; Son, D.; Klemm, U.; Mollenkopf, H.-J.; Herbst, H.; Mangler, M.; Vogel, J.; Saliba, A.-E.; Meyer, T. F.: Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia. Nature Cell Biology 23 (2), pp. 184 - 197 (2021)

Iftekhar, A.; Berger, H.; Bouznad, N.; Heuberger, J.; Boccellato, F.; Dobrindt, U.; Hermeking, H.; Sigal, M.; Meyer, T. F.: Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells. Nature Communications 12 (1), pp. 1 - 15 (2021)

Sepe, L. P.; Hartl, K.; Iftekhar, A.; Berger, H.; Kumar, N.; Goosmann, C.; Chopra, S.; Schmidt, S. C.; Gurumurthy, R. K.; Meyer, T. F. et al.; Boccellato, F.: Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells. mBio 11 (5), 01911-20. (2020)

Dziubanska-Kusibab, P. J.; Berger, H.; Battistini, F.; Bouwman, B. A. M.; Iftekhar, A.; Katainen, R.; Cajuso, T.; Crosetto, N.; Orozco, M.; Aaltonen, L. A. et al.; Meyer, T. F.: Colibactin DNA-damage signature indicates mutational impact in colorectal cancer. Nature Medicine 26 (7), pp. 1063 - 1069 (2020)

Hoffmann, K.; Berger, H.; Kulbe, H.; Thillainadarasan, S.; Mollenkopf, H.-J.; Zemojtel, T.; Taube, E.; Darb-Esfahani, S.; Mangler, M.; Sehouli, J. et al.; Chekerov, R.; Braicu, E. I.; Meyer, T. F.; Kessler, M.: Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment. EMBO Journal 39 (6), e104013 (2020)

Harnack, C.; Berger, H.; Antanaviciute, A.; Vidal, R.; Sauer, S.; Simmons, A.; Meyer, T. F.; Sigal, M.: R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon. Nature Communications 10 (1), 4368 (2019)

Sigal, M.; Reines, M. d. M.; Müllerke, S.; Fischer, C.; Kapalczynska, M.; Berger, H.; Bakker, E. R. M.; Mollenkopf, H.-J.; Rothenberg, M. E.; Wiedenmann, B. et al.; Meyer, T. F.: R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach. Nature Cell Biology 21 (7), pp. 812 - 823 (2019)

Kessler, M.; Hoffmann, K.; Fritsche, K.; Brinkmann, V.; Mollenkopf, H.-J.; Thieck, O.; Teixeira da Costa, A. R.; Braicu, E. I.; Sehouli, J.; Mangler, M. et al.; Berger, H.; Meyer, T. F.: Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation. Nature Communications 10 (1), 1194 (2019)

Boccellato, F.; Woelffling, S.; Imai-Matsushima, A.; Sanchez, G.; Goosmann, C.; Schmid, M.; Berger, H.; Morey, P.; Denecke, C.; Ordemann, J. et al.; Meyer, T. F.: Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection. Gut 68 (3), pp. 400 - 413 (2019)

Zadora, P. K.; Chumduri, C.; Imami, K.; Berger, H.; Mi, Y.; Selbach, M.; Meyer, T. F.; Gurumurthy, R. K.: Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to- Mesenchymal Transition in Host Cells. Cell Reports 26 (5), e8, pp. 1286 - 1302 (2019)

Imai-Matsushima, A.; Martin-Sancho, L.; Karlas, A.; Imai, S.; Zoranovic, T.; Hocke, A. C.; Mollenkopf, H.-J.; Berger, H.; Meyer, T. F.: Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies. EBioMedicine 33, pp. 230 - 241 (2018)

Sigal, M.; Logan, C. Y.; Kapalczynska, M.; Mollenkopf, H.-J.; Berger, H.; Wiedenmann, B.; Nusse, R.; Amieva, M. R.; Meyer, T.: Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis. Nature 548 (7668), pp. 451 - 455 (2017)

Berger, H.; Marques, M. S.; Zietlow, R.; Meyer, T. F.; Machado, J. C.; Figueiredo, C.: Gastric cancer pathogenesis. Helicobacter 21 (Suppl. 1), pp. 34 - 38 (2016)

Schlaermann, P.; Toelle, B.; Berger, H.; Schmidt, S. C.; Glanemann, M.; Ordemann, J.; Bartfeld, S.; Mollenkopf, H. J.; Meyer, T. F.: A novel human gastric primary cell culture system for modelling Helicobacter pylori infection in vitro. Gut 65 (2), pp. 202 - 213 (2016)

Herweg, J.-A.; Pons, V.; Becher, D.; Hecker, M.; Krohne, G.; Barbier, J.; Berger, H.; Rudel, T.; Mehlitz, A.: Proteomic analysis of the Simkania-containing vacuole: the central role of retrograde transport. Molecular Microbiology 99 (1), pp. 151 - 171 (2016)