Publications of Thumbi Ndung'u

Roider, J.; Porterfield, J. Z.; Ogongo, P.; Muenchhoff, M.; Adland, E.; Groll, A.; Morris, L.; Moore, P. L.; Ndung'u, T.; Kløverpris, H. et al.; Goulder, P. J. R.; Leslie, A.: Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children. Frontiers in immunology 10, 1497 (2019)

Lee, G. Q.; Reddy, K.; Einkauf, K. B.; Gounder, K.; Chevalier, J. M.; Dong, K. L.; Walker, B. D.; Yu, X. G.; Ndung'u, T.; Lichterfeld, M.: HIV-1 DNA sequence diversity and evolution during acute subtype C infection. Nature Communications 10 (1), 2737 (2019)

Wong, E. B.; Gold, M. C.; Meermeier, E. W.; Xulu, B. Z.; Khuzwayo, S.; Sullivan, Z. A.; Mahyari, E.; Rogers, Z.; Kløverpris, H.; Sharma, P. K. et al.; Worley, A. H.; Lalloo, U.; Baijnath, P.; Ambaram, A.; Naidoo, L.; Suleman, M.; Madansein, R.; McLaren, J. E.; Ladell, K.; Miners, K. L.; Price, D. A.; Behar, S. M.; Nielsen, M.; Kasprowicz, V. O.; Leslie, A.; Bishai, W. R.; Ndung'u, T.; Lewinsohn, D. M.: TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Communications Biology 2, 203 (2019)

Mori, M.; Leitman, E.; Walker, B.; Ndung'u, T.; Carrington, M.; Goulder, P.: Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa. The Journal of Infectious Diseases 219 (9), pp. 1456 - 1463 (2019)

Naidoo, L.; Mzobe, Z.; Jin, S. W.; Rajkoomar, E.; Reddy, T.; Brockman, M. A.; Brumme, Z. L.; Ndung'u, T.; Mann, J. K.: Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes. Virology 531, pp. 192 - 202 (2019)

Muenchhoff, M.; Adland, E.; Roider, J.; Kløverpris, H.; Leslie, A.; Boehm, S.; Keppler, O. T.; Ndung'u, T.; Goulder, P. J. R.: Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children. The Journal of Infectious Diseases 219 (9), pp. 1407 - 1417 (2019)

Akilimali, N. A.; Muema, D. M.; Specht, C.; Chang, C.; Moosa, M.-Y. S.; Levitz, S. M.; Lewin, S. R.; French, M. A.; Ndung'u, T.: Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome Is Associated With Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T Cells and Monocyte Activation. Journal of Acquired Immune Deficiency Syndromes 80 (5), pp. 596 - 604 (2019)

Naidoo, K. K.; Ngubane, A.; Gaza, P.; Moodley, A.; Ndung'u, T.; Thobakgale, C. F.: Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans. Frontiers in immunology 10, 551 (2019)

Roider, J.; Ngoepe, A.; Muenchhoff, M.; Adland, E.; Groll, A.; Ndung'u, T.; Kløverpris, H.; Goulder, P.; Leslie, A.: Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children. Frontiers in immunology 10, 213 (2019)

Yoon, H. A.; Nakouzi, A.; Chang, C. C.; Kuniholm, M. H.; Carreño, L. J.; Wang, T.; Ndung'u, T.; Lewin, S. R.; French, M. A.; Pirofski, L.-a.: Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome. The Journal of Infectious Diseases 219 (3), pp. 420 - 428 (2019)

Ogunshola, F.; Anmole, G.; Miller, R. L.; Goering, E.; Nkosi, T.; Muema, D.; Mann, J.; Ismail, N.; Chopera, D.; Ndung'u, T. et al.; Brockman, M. A.; Ndhlovu, Z. M.: Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants. Nature Communications 9 (1), 5023 (2018)

Kaida, A.; Dietrich, J. J.; Laher, F.; Beksinska, M.; Jaggernath, M.; Bardsley, M.; Smith, P.; Cotton, L.; Chitneni, P.; Closson, K. et al.; Lewis, D. A.; Smit, J. A.; Ndung'u, T.; Brockman, M.; Gray, G.: A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts. BMC Infectious Diseases 18 (1), 499 (2018)

Ojwach, D. B. A.; MacMillan, D.; Reddy, T.; Novitsky, V.; Brumme, Z. L.; Brockman, M. A.; Ndung'u, T.; Mann, J. K.: Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection. Journal of Virology 92 (19), e00811-18 (2018)

Ndung'u, T.; Dong, K. L.; Kwon, D. S.; Walker, B. D.: A FRESH approach: Combining basic science and social good. Science Immunology 3 (27), eaau2798 (2018)

Roider, J.; Maehara, T.; Ngoepe, A.; Ramsuran, D.; Muenchhoff, M.; Adland, E.; Aicher, T.; Kazer, S. W.; Jooste, P.; Karim, F. et al.; Kuhn, W.; Shalek, A. K.; Ndung'u, T.; Morris, L.; Moore, P. L.; Pillai, S.; Kløverpris, H.; Goulder, P.; Leslie, A.: High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults. Frontiers in immunology 9, 1975 (2018)

Baiyegunhi, O.; Ndlovu, B.; Ogunshola, F.; Ismail, N.; Walker, B. D.; Ndung'u, T.; Ndhlovu, Z. M.: Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load. Journal of Virology 92 (15), e00659-18 (2018)

Mvo, Z.; Ntlantsana, V.; Bengu, N.; Millar, J.; Roider, J.; Bhoola, R.; Krishna, M.; Graza, Y.; van Lobenstein, J.; Kapongo, C. et al.; Kogielambal, C.; Sprenger, K.; Archary, M.; Ndung'u, T.; Goulder, P.: Unmet needs of high-risk mothers reduce success of antiretroviral treatment in HIV-infected infants. South African Medical Journal 108 (8), pp. 609 - 610 (2018)

Sojane, K.; Kangethe, R. T.; Chang, C. C.; Moosa, M.-Y. S.; Lewin, S. R.; French, M. A.; Ndung'u, T.: Individuals with HIV-1 Subtype C Infection and Cryptococcal Meningitis Exhibit Viral Genetic Intermixing of HIV-1 Between Plasma and Cerebrospinal Fluid and a High Prevalence of CXCR4-Using Variants. AIDS Research and Human Retroviruses 34 (7), pp. 607 - 620 (2018)

Chung, A. W.; Mabuka, J. M.; Ndlovu, B.; Licht, A.; Robinson, H.; Ramlakhan, Y.; Ghebremichael, M.; Reddy, T.; Goulder, P. J.R.; Walker, B. D. et al.; Ndung'u, T.; Alter, G.: Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity. AIDS 32 (10), p. 1207-1217 (2018)

Naidoo, N.; Pillay, B.; Bubb, M.; Pym, A.; Chiliza, T.; Naidooe, K.; Ndung'u, T.; Kasprowicz, V. O.; Pillay, M.: Evaluation of a synthetic peptide for the detection of anti-Mycobacterium tuberculosis curli pili IgG antibodies in patients with pulmonary tuberculosis. Tuberculosis 109, pp. 80 - 84 (2018)