Publications of Thumbi Ndung'u

Journal Article (137)

2022
Journal Article
Bengu, N.; Mchunu, N.; Mokhethi, S.; Fillis, R.; Cromhout, G.; van Lobenstein, J.; Graza, Y.; Kapongo, C.; Chinniah, K.; Bhoola, R. et al.; Adland, E.; Puertas, M. C.; Ndung'u, T.; Martinez-Picado, J.; Archary, M.; Goulder, P. J. R.: Next-generation point-of-care testing in pediatric human immunodeficiency virus infection facilitates diagnosis and monitoring of treatment. MEDICINE 101 (27), e29228 (2022)
Journal Article
Ogunshola, F. J.; Smidt, W.; Naidoo, A. F.; Nkosi, T.; Ngubane, T.; Khaba, T.; Baiyegunhi, O. O.; Mahlobo, B.; Rasehlo, S.; Ngema, N. et al.; Jajbhay, I.; Dong, K. L.; Ramsuran, V.; Pansegrouw, J.; Ndung'u, T.; Walker, B. D.; de Oliveria, T.; Ndhlovu, Z. M.: Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD81 T cells into B-cell follicles during HIV-1 infection. Blood Adv 6 (6), pp. 1904 - 1916 (2022)
Journal Article
Bloom, S. M.; Mafunda, N. A.; Woolston, B. M.; Hayward, M. R.; Frempong, J. F.; Abai, A. B.; Xu, J.; Mitchell, A. J.; Westergaard, X.; Hussain, F. A. et al.; Xulu, N.; Dong, M.; Dong, K. L.; Gumbi, T.; Ceasar, F. X.; Rice, J. K.; Choksi, N.; Ismail, N.; Ndung'u, T.; Ghebremichael, M. S.; Relman, D. A.; Balskus, E. P.; Mitchell, C. M.; Kwon, D. S.: Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nature Microbiology 7, pp. 434 - 450 (2022)
2021
Journal Article
Singer, S. N.; Ndumnego, O. C.; Kim, R. S.; Ndung'u, T.; Anastos, K.; French, A.; Churchyard, G.; Paramithiothis, E.; Kasprowicz, V. O.; Achkar, J. M.: Plasma host protein biomarkers correlating with increasing Mycobacterium tuberculosis infection activity prior to tuberculosis diagnosis in people living with HIV. EBioMedicine 75, 103787 (2021)
Journal Article
Olivier, S.; Murray, T.; Matthews, P.; Mhlongo, N.; Gunda, R.; Baisley, K.; Gareta, D.; Modise, T.; Smit, T.; Herbst, K. et al.; Mpofana, X.; Ndung'u, T.; Koole, O.; Pillay, D.; Hanekom, W.; Wong, E.; Siedner, M. J.; team, V. S.: Pitfalls of Single Measurement Screening for Diabetes and Hypertension in Community-Based Settings. Glob Heart 16 (1) (2021)
Journal Article
Millar, J. R.; Bengu, N.; Vieira, V. A.; Adland, E.; Roider, J.; Muenchhoff, M.; Fillis, R.; Sprenger, K.; Ntlantsana, V.; Fatti, I. et al.; Archary, M.; Groll, A.; Ismail, N.; García-Guerrero, M. C.; Matthews, P. C.; Ndung'u, T.; Puertas, M. C.; Martinez-Picado, J.; Goulder, P.: Early Initiation of Antiretroviral Therapy Following In Utero HIV Infection Is Associated With Low Viral Reservoirs but Other Factors Determine Viral Rebound. J Infect Dis 224 (11), pp. 1925 - 1934 (2021)
Journal Article
Gunda, R.; Koole, O.; Gareta, D.; Olivier, S.; Surujdeen, A.; Smit, T.; Modise, T.; Dreyer, J.; Ording-Jespersen, G.; Munatsi, D. et al.; Nxumalo, S.; Khoza, T.; Mhlongo, N.; Baisley, K.; Seeley, J.; Grant, A. D.; Herbst, K.; Ndung'u, T.; Hanekom, W. A.; Siedner, M. J.; Pillay, D.; Wong, E. B.; Vukuzazi Study Team: Cohort Profile: The Vukuzazi ('Wake Up and Know Yourself' in isiZulu) population science programme. International Journal of Epidemiology (2021)
Journal Article
Asowata, O. E.; Singh, A.; Ngoepe, A.; Herbert, N.; Fardoos, R.; Reddy, K.; Zungu, Y.; Nene, F.; Mthabela, N.; Ramjit, D. et al.; Karim, F.; Govender, K.; Ndung'u, T.; Porterfield, J. Z.; Adamson, J. H.; Madela, F. G.; Manzini, V. T.; Anderson, F.; Leslie, A.; Kløverpris, H. N.: Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection. JCI Insight. 6 (22), e146162 (2021)
Journal Article
Vieira, V. A.; Adland, E.; Malone, D. F. G.; Martin, M. P.; Groll, A.; Ansari, M. A.; Garcia-Guerrero, M. C.; Puertas, M. C.; Muenchhoff, M.; Guash, C. F. et al.; Brander, C.; Martinez-Picado, J.; Bamford, A.; Tudor-Williams, G.; Ndung'u, T.; Walker, B. D.; Ramsuran, V.; Frater, J.; Jooste, P.; Peppa, D.; Carrington, M.; Goulder, P. J. R.: An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults. PLoS Pathogens 17 (11), e1010090 (2021)
Journal Article
Nduati, E. W.; Gorman, M. J.; Sein, Y.; Hermanus, T.; Yuan, D.; Oyaro, I.; Muema, D. M.; Ndung'u, T.; Alter, G.; Moore, P. L.: Coordinated Fc-effector and neutralization functions in HIV-infected children define a window of opportunity for HIV vaccination. AIDS 35 (12) (2021)
Journal Article
Naidoo, K. K.; Ndumnego, O. C.; Ismail, N.; Dong, K. L.; Ndung'u, T.: Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection. Frontiers in immunology 12, 738743 (2021)
Journal Article
Byrne, E. H.; Farcasanu, M.; Bloom, S. M.; Xulu, N.; Xu, J.; Jr, B. L. H.; Mafunda, N. A.; Hayward, M. R.; Dong, M.; Dong, K. L. et al.; Gumbi, T.; Ceasar, F. X.; Ismail, N.; Ndung'u, T.; Gosmann, C.; Ghebremichael, M. S.; Handley, S. A.; Mitchell, C. M.; Villani, A.-C.; Kwon, D. S.: Antigen Presenting Cells Link theFemale Genital Tract Microbiometo Mucosal Inflammation, WithHormonal Contraception as anAdditional Modulator ofInflammatory Signatures. Frontiers in Cellular and Infection Microbiology 11, 733619 (2021)
Journal Article
Hassan, A. S.; Hare, J.; Gounder, K.; Nazziwa, J.; Karlson, S.; Olsson, L.; Streatfield, C.; Kamali, A.; Karita, E.; Kilembe, W. et al.; Price, M. A.; Borrow, P.; Björkman, P.; Kaleebu, P.; Allen, S.; Hunter, E.; Ndung'u, T.; Gilmour, J.; Rowland-Jones, S.; Esbjörnsson, J.; Sanders, E. J.: A Stronger Innate Immune Response During Hyperacute Human Immunodeficiency Virus Type 1 (HIV-1) Infection Is Associated With Acute Retroviral Syndrome. Clin Infect Dis 73 (5), pp. 832 - 841 (2021)
Journal Article
Snyman, J.; Hwa, S.-H.; Krause, R.; Muema, D.; Reddy, T.; Ganga, Y.; Karim, F.; Leslie, A.; Sigal, A.; Ndung'u, T. et al.; Team, C.-K.: Similar antibody responses against SARS-CoV-2 in HIV uninfected and infected individuals on antiretroviral therapy during the first South African infection wave. Clinical Infectious Diseases, ciab758 (2021)
Journal Article
Millar, J. R.; Fatti, I.; Mchunu, N.; Bengu, N.; Grayson, N. E.; Adland, E.; Bonsall, D.; Archary, M.; Matthews, P. C.; Ndung'u, T. et al.; Goulder, P.: Second-generation mother-to-child HIV transmission in South Africa is characterized by poor outcomes. AIDS 35 (10), pp. 1597 - 1604 (2021)
Journal Article
Munoz, A.; Hayward, M. R.; Bloom, S. M.; Rocafort, M.; Ngcapu, S.; Mafunda, N. A.; Xu, J.; Xulu, N.; Dong, M.; Dong, K. L. et al.; Ismail, N.; Ndung'u, T.; Kwon, M. S. G. D. S.: Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health. Microbiome 9 (1) (2021)
Journal Article
Wong, E. B.; Olivier, S.; Gunda, R.; Koole, O.; Surujdeen, A.; Gareta, D.; Munatsi, D.; Modise, T. H.; Dreyer, J.; Nxumalo, S. et al.; Smit, T. K.; Ording-Jespersen, G.; Mpofana, I. B.; Khan, K.; Sikhosana, Z. E. L.; Moodley, S.; Shen, Y.-J.; Khoza, T.; Mhlongo, N.; Bucibo, S.; Nyamande, K.; Baisley, K. J.; Cuadros, D.; Tanser, F.; Grant, A. D.; Herbst, K.; Seeley, J.; Hanekom, W. A.; Ndung'u, T.; Siedner, M. J.; Pillay, D.; Team, V.: Convergence of infectious and non-communicable disease epidemics in rural South Africa: a cross-sectional, population-based multimorbidity study. The Lancet Global Health 9 (7), pp. e967 - e976 (2021)
Journal Article
Fehr, J.; Konigorski, S.; Olivier, S.; Gunda, R.; Surujdeen, A.; Gareta, D.; Smit, T.; Baisley, K.; Moodley, S.; Moosa, Y. et al.; Hanekom, W.; Koole, O.; Ndung'u, T.; Pillay, D.; Grant, A. D.; Siedner, M. J.; Lippert, C.; Wong, E. B.; Team, V.: Computer-aided interpretation of chest radiography reveals the spectrum of tuberculosis in rural South Africa. NPJ Digit Med 4 (1) (2021)
Journal Article
Jesson, J.; Dietrich, J.; Beksinska, M.; Closson, K.; Nduna, M.; Smit, J.; Brockman, M.; Ndung'u, T.; Gray, G.; Kaida, A.: Food insecurity and depression: a cross-sectional study of a multi-site urban youth cohort in Durban and Soweto, South Africa. TROPICAL MEDICINE & INTERNATIONAL HEALTH 26 (6), pp. 687 - 700 (2021)
Journal Article
Farinre, O.; Gounder, K.; Reddy, T.; Tongo, M.; Hare, J.; Chaplin, B.; Gilmour, J.; Kanki, P.; Mann, J. K.; Ndung'u, T.: Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa. Retrovirology 18 (1) (2021)
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