Publications of Alexander Karlas

Journal Article (25)

2020
Journal Article
Dekel, N.; Eisenberg-Domovich, Y.; Karlas, A.; Meyer, T. F.; Bracher, F.; Lebendiker, M.; Danieli, T.; Livnah, O.: Expression, purification and crystallization of CLK1 kinase – A potential target for antiviral therapy. Protein Expression and Purification 176, 105742 (2020)
2019
Journal Article
Artarini, A.; Meyer, M.; Shin, Y. J.; Huber, K.; Hilz, N.; Bracher, F.; Eros, D.; Orfi, L.; Keri, G.; Goedert, S. et al.; Neuenschwander, M.; von Kries, J.; Domovich-Eisenberg, Y.; Dekel, N.; Szabadkai, I.; Lebendiker, M.; Horváth, Z.; Danieli, T.; Livnah, O.; Moncorgé, O.; Frise, R.; Barclay, W.; Meyer, T. F.; Karlas, A.: Regulation of influenza a virus mRNA splicing by CLK1. Antiviral Research 168, pp. 187 - 196 (2019)
Journal Article
Laske, T.; Bachmann, M.; Dostert, M.; Karlas, A.; Wirth, D.; Frensing, T.; Meyer, T. F.; Hauser, H.; Reichl, U.: Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth. PLoS Computational Biology 15 (4), e1006944 (2019)
Journal Article
Lesch, M.; Luckner, M.; Meyer, M.; Weege, F.; Gravenstein, I.; Raftery, M.; Sieben, C.; Martin-Sancho, L.; Imai-Matsushima, A.; Welke, R.-W. et al.; Frise, R.; Barclay, W.; Schönrich, G.; Herrmann, A.; Meyer, T. F.; Karlas, A.: RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals. PLoS Pathogens 15 (3), e1007601 (2019)
2018
Journal Article
Imai-Matsushima, A.; Martin-Sancho, L.; Karlas, A.; Imai, S.; Zoranovic, T.; Hocke, A. C.; Mollenkopf, H.-J.; Berger, H.; Meyer, T. F.: Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies. EBioMedicine 33, pp. 230 - 241 (2018)
2017
Journal Article
Zimmermann, S.; Pfannkuch, L.; Al-Zeer, M. A.; Bartfeld, S.; Koch, M.; Liu, J.; Rechner, C.; Soerensen, M.; Sokolova, O.; Zamyatina, A. et al.; Kosma, P.; Mäurer, A. P.; Glowinski, F.; Pleissner, K.-P.; Schmid, M.; Brinkmann, V.; Karlas, A.; Naumann, M.; Rother, M.; Machuy, N.; Meyer, T. F.: ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System. Cell Reports 20 (10), pp. 2384 - 2395 (2017)
Journal Article
Sadewasser, A.; Paki, K.; Eichelbaum, K.; Bogdanow, B.; Saenger, S.; Budt, M.; Lesch, M.; Hinz, K.-P.; Herrmann, A.; Meyer, T. F. et al.; Karlas, A.; Selbach, M.; Wolff, a. T.: Quantitative Proteomic Approach Identifies Vpr Binding Protein as Novel Host Factor Supporting Influenza A Virus Infections in Human Cells. Molecular and Cellular Proteomics 16 (5), pp. 728 - 742 (2017)
2016
Journal Article
Karlas, A.; Berre, S.; Couderc, T.; Varjak, M.; Braun, P.; Meyer, M.; Gangneux, N.; Karo-Astover, L.; Weege, F.; Raftery, M. et al.; Schönrich, G.; Klemm, U.; Wurzlbauer, A.; Bracher, F.; Merits, A.; Meyer, T. F.; Lecuit, M.: A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. Nature Communications 7, 11320 (2016)
Journal Article
Wörmann, X.; Lesch, M.; Welke, R.-W.; Okonechnikov, K.; Abdurishid, M.; Sieben, C.; Geissner, A.; Brinkmann, V.; Kastner, M.; Karner, A. et al.; Zhu, R.; Hinterdorfer, P.; Anish, C.; Seeberger, P. H.; Herrmann, A.; Meyer, T. F.; Karlas, A.: Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology 492, pp. 118 - 129 (2016)
2015
Journal Article
Tripathi, S.; Pohl, M. O.; Zhou, Y.; Rodriguez-Frandsen, A.; Wang, G.; Stein, D. A.; Moulton, H. M.; DeJesus, P.; Che, J.; Mulder, L. C.F. et al.; Yángüez, E.; Andenmatten, D.; Pache, L.; Manicassamy, B.; Albrecht, R. A.; Gonzalez, M. G.; Nguyen, Q.; Brass, A.; Elledge, S.; White, M.; Shapira, S.; Hacohen, N.; Karlas, A.; Meyer, T. F.; Shales, M.; Gatorano, A.; Johnson, J. R.; Jang, G.; Johnson, T.; Verschueren, E.; Sanders, D.; Krogan, N.; Shaw, M.; König, R.; Stertz, S.; García-Sastre, A.; Chanda, S. K.: Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding. Cell Host & Microbe 18 (6), pp. 723 - 735 (2015)
2014
Journal Article
Gurumurthy, R. K.; Chumduri, C.; Karlas, A.; Kimmig, S.; Gonzalez, E.; Machuy, N.; Rudel, T.; Meyer, T. F.: Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development. Molecular Microbiology 94 (1), pp. 186 - 201 (2014)
Journal Article
Winterling, C.; Koch, M.; Koeppel, M.; García-Alcalde, F.; Karlas, A.; Meyer, T. F.: Evidence for a crucial role of a host non-coding RNA in influenza A virus replication. RNA Biology 11 (1), pp. 66 - 75 (2014)
2013
Journal Article
Glatzer, T.; Killig, M.; Meisig, J.; Ommert, I.; Luetke-Eversloh, M.; Babic, M.; Paclik, D.; Blüthgen, N.; Seidl, R.; Seifarth, C. et al.; Gröne, J.; Lenarz, M.; Stölzel, K.; Fugmann, D.; Porgador, A.; Hauser, A.; Karlas, A.; Romagnani, C.: RORγt+ Innate Lymphoid Cells Acquire a Proinflammatory Program upon Engagement of the Activating Receptor NKp44. Immunity 38 (6), pp. 1223 - 1235 (2013)
2011
Journal Article
Csordas, A.; Kreutmayer, S.; Ploner, C.; Braun, P. R.; Karlas, A.; Backovic, A.; Wick, G.; Bernhard, D.: Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells. Cardiovascular Research 92 (1), pp. 141 - 148 (2011)
Journal Article
Al-Younes, H. M.; Al-Zeer, M. A.; Khalil, H.; Gussmann, J.; Karlas, A.; Machuy, N.; Brinkmann, V.; Braun, P. R.; Meyer, T. F.: Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis. Autophagy 7 (8), pp. 814 - 828 (2011)
Journal Article
Al-Younes, H. M.; Al-Zeer, M. A.; Khalil, H.; Gussmann, J.; Karlas, A.; Machuy, N.; Brinkmann, V.; Braun, P. R.; Meyer, T. F.: Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis. Autophagy 7 (8), pp. 814 - 828 (2011)
2010
Journal Article
Nielsen, E. J. B.; Nielsen, J. M.; Becker, D.; Karlas, A.; Prakash, H.; Glud, S. Z.; Merrison, J.; Besenbacher, F.; Meyer, T. F.; Kjems, J. et al.; Howard, K. A.: Pulmonary Gene Silencing in Transgenic EGFP Mice Using Aerosolised Chitosan/siRNA Nanoparticles. Pharmaceutical Research 27 (12), pp. 2520 - 2527 (2010)
Journal Article
Fehri, L. F.; Koch, M.; Belogolova, E.; Khalil, H.; Bolz, C.; Kalali, B.; Mollenkopf, H. J.; Beigier-Bompadre, M.; Karlas, A.; Schneider, T. et al.; Churin, Y.; Gerhard, M.; Meyer, T. F.: Helicobacter pylori Induces miR-155 in T Cells in a cAMP-Foxp3-Dependent Manner. PLoS ONE 5 (3), e9500 (2010)
Journal Article
Fehri, L. F.; Koch, M.; Belogolova, E.; Khalil, H.; Bolz, C.; Kalali, B.; Mollenkopf, H. J.; Beigier-Bompadre, M.; Karlas, A.; Schneider, T. et al.; Churin, Y.; Gerhard, M.; Meyer, T. F.: Helicobacter pylori Induces miR-155 in T Cells in a cAMP-Foxp3-Dependent Manner. PLoS ONE 5 (3), e9500 (2010)
Journal Article
Karlas, A.; Machuy, N.; Shin, Y.; Pleissner, K.-P.; Artarini, A.; Heuer, D.; Becker, D.; Khalil, H.; Ogilvie, L. A.; Hess, S. et al.; Mäurer, A. P.; Müller, E.; Wolff, T.; Rudel, T.; Meyer, T. F.: Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature 463 (7282), pp. 818 - 822 (2010)
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