Publications of Alexander Karlas

Kastner, M.; Karner, A.; Zhu, R.; Huang, Q.; Geissner, A.; Sadewasser, A.; Lesch, M.; Wörmann, X.; Karlas, A.; Seeberger, P. H. et al.; Wolff, T.; Hinterdorfer, P.; Herrmann, A.; Sieben, C.: Relevance of Host Cell Surface Glycan Structure for Cell Specificity of Influenza A Viruses. Viruses 15 (7), 1507 (2023)

Dekel, N.; Eisenberg-Domovich, Y.; Karlas, A.; Meyer, T. F.; Bracher, F.; Lebendiker, M.; Danieli, T.; Livnah, O.: Expression, purification and crystallization of CLK1 kinase – A potential target for antiviral therapy. Protein Expression and Purification 176, 105742 (2020)

Artarini, A.; Meyer, M.; Shin, Y. J.; Huber, K.; Hilz, N.; Bracher, F.; Eros, D.; Orfi, L.; Keri, G.; Goedert, S. et al.; Neuenschwander, M.; von Kries, J.; Domovich-Eisenberg, Y.; Dekel, N.; Szabadkai, I.; Lebendiker, M.; Horváth, Z.; Danieli, T.; Livnah, O.; Moncorgé, O.; Frise, R.; Barclay, W.; Meyer, T. F.; Karlas, A.: Regulation of influenza a virus mRNA splicing by CLK1. Antiviral Research 168, pp. 187 - 196 (2019)

Laske, T.; Bachmann, M.; Dostert, M.; Karlas, A.; Wirth, D.; Frensing, T.; Meyer, T. F.; Hauser, H.; Reichl, U.: Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth. PLoS Computational Biology 15 (4), e1006944 (2019)

Lesch, M.; Luckner, M.; Meyer, M.; Weege, F.; Gravenstein, I.; Raftery, M.; Sieben, C.; Martin-Sancho, L.; Imai-Matsushima, A.; Welke, R.-W. et al.; Frise, R.; Barclay, W.; Schönrich, G.; Herrmann, A.; Meyer, T. F.; Karlas, A.: RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals. PLoS Pathogens 15 (3), e1007601 (2019)

Imai-Matsushima, A.; Martin-Sancho, L.; Karlas, A.; Imai, S.; Zoranovic, T.; Hocke, A. C.; Mollenkopf, H.-J.; Berger, H.; Meyer, T. F.: Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies. EBioMedicine 33, pp. 230 - 241 (2018)

Zimmermann, S.; Pfannkuch, L.; Al-Zeer, M. A.; Bartfeld, S.; Koch, M.; Liu, J.; Rechner, C.; Soerensen, M.; Sokolova, O.; Zamyatina, A. et al.; Kosma, P.; Mäurer, A. P.; Glowinski, F.; Pleissner, K.-P.; Schmid, M.; Brinkmann, V.; Karlas, A.; Naumann, M.; Rother, M.; Machuy, N.; Meyer, T. F.: ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System. Cell Reports 20 (10), pp. 2384 - 2395 (2017)

Sadewasser, A.; Paki, K.; Eichelbaum, K.; Bogdanow, B.; Saenger, S.; Budt, M.; Lesch, M.; Hinz, K.-P.; Herrmann, A.; Meyer, T. F. et al.; Karlas, A.; Selbach, M.; Wolff, a. T.: Quantitative Proteomic Approach Identifies Vpr Binding Protein as Novel Host Factor Supporting Influenza A Virus Infections in Human Cells. Molecular and Cellular Proteomics 16 (5), pp. 728 - 742 (2017)

Karlas, A.; Berre, S.; Couderc, T.; Varjak, M.; Braun, P.; Meyer, M.; Gangneux, N.; Karo-Astover, L.; Weege, F.; Raftery, M. et al.; Schönrich, G.; Klemm, U.; Wurzlbauer, A.; Bracher, F.; Merits, A.; Meyer, T. F.; Lecuit, M.: A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs. Nature Communications 7, 11320 (2016)

Wörmann, X.; Lesch, M.; Welke, R.-W.; Okonechnikov, K.; Abdurishid, M.; Sieben, C.; Geissner, A.; Brinkmann, V.; Kastner, M.; Karner, A. et al.; Zhu, R.; Hinterdorfer, P.; Anish, C.; Seeberger, P. H.; Herrmann, A.; Meyer, T. F.; Karlas, A.: Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells. Virology 492, pp. 118 - 129 (2016)

Tripathi, S.; Pohl, M. O.; Zhou, Y.; Rodriguez-Frandsen, A.; Wang, G.; Stein, D. A.; Moulton, H. M.; DeJesus, P.; Che, J.; Mulder, L. C.F. et al.; Yángüez, E.; Andenmatten, D.; Pache, L.; Manicassamy, B.; Albrecht, R. A.; Gonzalez, M. G.; Nguyen, Q.; Brass, A.; Elledge, S.; White, M.; Shapira, S.; Hacohen, N.; Karlas, A.; Meyer, T. F.; Shales, M.; Gatorano, A.; Johnson, J. R.; Jang, G.; Johnson, T.; Verschueren, E.; Sanders, D.; Krogan, N.; Shaw, M.; König, R.; Stertz, S.; García-Sastre, A.; Chanda, S. K.: Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding. Cell Host & Microbe 18 (6), pp. 723 - 735 (2015)

Gurumurthy, R. K.; Chumduri, C.; Karlas, A.; Kimmig, S.; Gonzalez, E.; Machuy, N.; Rudel, T.; Meyer, T. F.: Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development. Molecular Microbiology 94 (1), pp. 186 - 201 (2014)

Winterling, C.; Koch, M.; Koeppel, M.; García-Alcalde, F.; Karlas, A.; Meyer, T. F.: Evidence for a crucial role of a host non-coding RNA in influenza A virus replication. RNA Biology 11 (1), pp. 66 - 75 (2014)

Glatzer, T.; Killig, M.; Meisig, J.; Ommert, I.; Luetke-Eversloh, M.; Babic, M.; Paclik, D.; Blüthgen, N.; Seidl, R.; Seifarth, C. et al.; Gröne, J.; Lenarz, M.; Stölzel, K.; Fugmann, D.; Porgador, A.; Hauser, A.; Karlas, A.; Romagnani, C.: RORγt+ Innate Lymphoid Cells Acquire a Proinflammatory Program upon Engagement of the Activating Receptor NKp44. Immunity 38 (6), pp. 1223 - 1235 (2013)

Csordas, A.; Kreutmayer, S.; Ploner, C.; Braun, P. R.; Karlas, A.; Backovic, A.; Wick, G.; Bernhard, D.: Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells. Cardiovascular Research 92 (1), pp. 141 - 148 (2011)

Al-Younes, H. M.; Al-Zeer, M. A.; Khalil, H.; Gussmann, J.; Karlas, A.; Machuy, N.; Brinkmann, V.; Braun, P. R.; Meyer, T. F.: Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis. Autophagy 7 (8), pp. 814 - 828 (2011)

Al-Younes, H. M.; Al-Zeer, M. A.; Khalil, H.; Gussmann, J.; Karlas, A.; Machuy, N.; Brinkmann, V.; Braun, P. R.; Meyer, T. F.: Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis. Autophagy 7 (8), pp. 814 - 828 (2011)

Nielsen, E. J. B.; Nielsen, J. M.; Becker, D.; Karlas, A.; Prakash, H.; Glud, S. Z.; Merrison, J.; Besenbacher, F.; Meyer, T. F.; Kjems, J. et al.; Howard, K. A.: Pulmonary Gene Silencing in Transgenic EGFP Mice Using Aerosolised Chitosan/siRNA Nanoparticles. Pharmaceutical Research 27 (12), pp. 2520 - 2527 (2010)

Fehri, L. F.; Koch, M.; Belogolova, E.; Khalil, H.; Bolz, C.; Kalali, B.; Mollenkopf, H. J.; Beigier-Bompadre, M.; Karlas, A.; Schneider, T. et al.; Churin, Y.; Gerhard, M.; Meyer, T. F.: Helicobacter pylori Induces miR-155 in T Cells in a cAMP-Foxp3-Dependent Manner. PLoS ONE 5 (3), e9500 (2010)

Fehri, L. F.; Koch, M.; Belogolova, E.; Khalil, H.; Bolz, C.; Kalali, B.; Mollenkopf, H. J.; Beigier-Bompadre, M.; Karlas, A.; Schneider, T. et al.; Churin, Y.; Gerhard, M.; Meyer, T. F.: Helicobacter pylori Induces miR-155 in T Cells in a cAMP-Foxp3-Dependent Manner. PLoS ONE 5 (3), e9500 (2010)