Publications of Alex Sigal
All genres
Journal Article (43)
2022
Journal Article
Milder disease with Omicron: is it the virus or the pre-existing immunity? Nature Reviews Immunology (2022)
2021
Journal Article
12, 757134 (2021)
Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response. Frontiers in Microbiology
Journal Article
4 (1) (2021)
Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology. Commun Biol.
Journal Article
10, e67397 (2021)
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave. eLife
Journal Article
9, e1009871 (2021)
T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy. PLoS Pathogens
Journal Article
Similar antibody responses against SARS-CoV-2 in HIV uninfected and infected individuals on antiretroviral therapy during the first South African infection wave. Clinical Infectious Diseases, ciab758 (2021)
Journal Article
12 (1) (2021)
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern. Nature Communications
Journal Article
Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains. eLife, e69317 (2021)
Journal Article
384 (20), pp. 1885 - 1898 (2021)
Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant. The New England Journal of Medicine: NEJM / Publ. by the Massachusetts Medical Society
Journal Article
593 (7857), pp. 142 - 146 (2021)
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma. Nature
Journal Article
184 (9), pp. 2372 - 2383 (2021)
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell
Journal Article
592 (7854), pp. 438 - 443 (2021)
Detection of a SARS-CoV-2 variant of concern in South Africa. Nature
Journal Article
Sixteen novel lineages of SARS-CoV-2 in South Africa. Nature Medicine (2021)
2020
Journal Article
2020, 001424 (2020)
Betamethasone induces potent immunosuppression and reduces HIV infection in a PBMC in vitro model. Journal of Investigative Medicine
Journal Article
11, 435 (2020)
Metformin as Host-Directed Therapy for TB Treatment: Scoping Review. Frontiers in Microbiology
Journal Article
16 (2), e1007482 (2020)
Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition. PLoS Computational Biology 2019
Journal Article
10, 1705 (2019)
Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model. Frontiers in immunology 2018
Journal Article
8, 263 (2018)
Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA. Frontiers in Cellular and Infection Microbiology
Journal Article
7, e30134 (2018)
Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. eLife
Journal Article
13 (1), e0189945 (2018)
Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner. PLoS One