Publikationen von Rajendra Kumar Gurumurthy

Kumar, N.; Prakash, P. G.; Wentland, C.; Kurian, S. M.; Jethva, G.; Brinkmann, V.; Mollenkopf, H.-J.; Krammer, T.; Toussaint, C.; Saliba, A.-E. et al.; Biebl, M.; Jürgensen, C.; Wiedenmann, B.; Meyer, T. F.; Gurumurthy, R. K.; Chumduri, C.: Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis. Nature Communications 15 (1), 3064 (2024)

Gurumurthy, R. K.; Kumar, N.; Chumduri, C.: Culturing and Differentiation of Patient-Derived Ectocervical Epithelial Stem Cells Using Air-Liquid Interphase and Matrigel Scaffold. Methods in Molecular Biology 2749, S. 109 - 121 (2023)

Dong, J.; Holthaus, D.; Peters, C.; Koster, S.; Ehsani, M.; Quevedo-Olmos, A.; Berger, H.; Zarobkiewicz, M.; Mangler, M.; Gurumurthy, R. K. et al.; Hedemann, N.; Chumduri, C.; Kabelitz, D.; Meyer, T. F.: γδ T cell-mediated cytotoxicity against patient-derived healthy and cancer cervical organoids. Frontiers in Immunology 14, 1281646. (2023)

Gurumurthy, R. K.; Pleissner, K.-P.; Chumduri, C.; Meyer, T. F.; Mäurer, A. P.: Single object profiles regression analysis (SOPRA): a novel method for analyzing high-content cell-based screens. BMC Bioinformatics 23 (1), 440 (2022)

Gurumurthy, R. K.; Koster, S.; Kumar, N.; Meyer, T. F.; Chumduri, C.: Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection. Nature Protocols, 1030 (2022)

Koster, S.; Gurumurthy, R. K.; Kumar, N.; Prakash, P. G.; Dhanraj, J.; Bayer, , S.; Berger, H.; Kurian, S. M.; Drabkina, M.; Mollenkopf, H.-J. et al.; Goosmann, C.; Brinkmann, V.; Nagel, Z.; Mangler, M.; Meyer, T. F.; Chumduri, C.: Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming. Nature Communications 13 (1) (2022)

Gurumurthy, R. K.; Kumar, N.; Chumduri, C.: Optimized protocol for isolation of high-quality single cells from the female mousereproductive tract tissues for single-cell RNAsequencing. STAR Protoc 2 (4), 100970 (2021)

Gurumurthy, R. K.; Kumar, N.; Chumduri, C.: Spatial analysis of organ-wide RNA, protein expression, and lineage tracing in the female mouse reproductive tract. STAR Protocols 2 (4), 100969 (2021)

Chumduri, C.; Gurumurthy, R. K.; Berger, H.; Dietrich, O.; Kumar, N.; Koster, S.; Brinkmann, V.; Hoffmann, K.; Drabkina, M.; Arampatzi, P. et al.; Son, D.; Klemm, U.; Mollenkopf, H.-J.; Herbst, H.; Mangler, M.; Vogel, J.; Saliba, A.-E.; Meyer, T. F.: Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia. Nature Cell Biology 23 (2), S. 184 - 197 (2021)

Sepe, L. P.; Hartl, K.; Iftekhar, A.; Berger, H.; Kumar, N.; Goosmann, C.; Chopra, S.; Schmidt, S. C.; Gurumurthy, R. K.; Meyer, T. F. et al.; Boccellato, F.: Genotoxic Effect of Salmonella Paratyphi A Infection on Human Primary Gallbladder Cells. mBio 11 (5), 01911-20. (2020)

Zadora, P. K.; Chumduri, C.; Imami, K.; Berger, H.; Mi, Y.; Selbach, M.; Meyer, T. F.; Gurumurthy, R. K.: Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to- Mesenchymal Transition in Host Cells. Cell Reports 26 (5), e8, S. 1286 - 1302 (2019)

Mi, Y.; Gurumurthy, R. K.; Zadora, P. K.; Meyer, T. F.; Chumduri, C.: Chlamydia trachomatis inhibits homologous recombination repair of DNA breaks by interfering with PP2A signaling. mBio 9 (6), e01465-18 (2018)

Rother, M.; Gonzalez, E.; Teixeira da Costa, A. R.; Wask, L.; Gravenstein, I.; Pardo, M.; Pietzke, M.; Gurumurthy, R. K.; Angermann, J.; Laudeley, R. et al.; Glage, S.; Meyer, M.; Chumduri, C.; Kempa, S.; Dinkel, K.; Unger, A.; Klebl, B.; Klos, A.; Meyer, T. F.: Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection. Cell Host & Microbe 23 (5), S. 661 - 671 (2018)

Chumduri, C.; Gurumurthy, R. K.; Zietlow, R.; Meyer, T. F.: Subversion of host genome integrity by bacterial pathogens. Nature Reviews Molecular Cell Biology 17 (10), S. 659 - 673 (2016)

Gurumurthy, R. K.; Chumduri, C.; Karlas, A.; Kimmig, S.; Gonzalez, E.; Machuy, N.; Rudel, T.; Meyer, T. F.: Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development. Molecular Microbiology 94 (1), S. 186 - 201 (2014)

Chumduri, C.; Gurumurthy, R. K.; Zadora, P. K.; Mi, Y.; Meyer, T. F.: Chlamydia Infection Promotes Host DNA Damage and Proliferation but Impairs the DNA Damage Response. Cell Host & Microbe 13 (6), S. 746 - 758 (2013)

Gurumurthy, R. K.; Mäurer, A. P.; Machuy, N.; Hess, S.; Pleissner, K.-P.; Schuchhardt, J.; Rudel, T.; Meyer, T. F.: A Loss-of-Function Screen Reveals Ras- and Raf-Independent MEK-ERK Signaling During Chlamydia trachomatis Infection. Science Signaling 3 (113), ra21 (2010)

Gurumurthy, R. K.; Mäurer, A. P.; Machuy, N.; Hess, S.; Pleissner, K.-P.; Schuchhardt, J.; Rudel, T.; Meyer, T. F.: A Loss-of-Function Screen Reveals Ras- and Raf-Independent MEK-ERK Signaling During Chlamydia trachomatis Infection. Science Signaling 3 (113), ra21 (2010)

Paland, N.; Böhme, L.; Gurumurthy, R. K.; Mäurer, A. P.; Szczepek, A. J.; Rudel, T.: Reduced display of tumor necrosis factor receptor I at the host cell surface supports infection with Chlamydia trachomatis. Journal of Biological Chemistry 283 (10), S. 6438 - 6448 (2008)